Importance Of Good Laboratory Practice (glp)
Good Laboratory Practice (GLP), or good laboratory practice, is a set guidelines that guide the planning, execution, monitoring, recording, reporting, and preservation of laboratory studies. This is not the same as laboratory safety standards (such a suitable clothing). GLP can be used to guarantee the credibility of submitted data and their traceability. This helps address the issue with non-reproducibility of many biopharmaceutical trials. GLP is intended for minimizing adverse drug reactions and improving environmental and human safety. GLP is a transparent and precise way to document laboratory work, assign responsibility and improve accountability. GLP is also recommended by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use.
GLP Tips
Follow and implement Standard Operating Procedures in your laboratory
SOPs regarding inspection, maintenance. Calibration and Testing
SOPs minimize inter-individual, inter-test variability and make reporting simpler.
Separation of activities
To minimise disturbances
Label all reagents with the names of the solutions, date of opening and storage conditions.
Use and obtain reagents in accordance with the relevant SOPs
Ensure that all animal studies on the species are done.
This allows for proper dosage selection
Validate all methods and instruments
All data must be linked to their sources and samples
The patient/subject information should be included on the label of each sample, as per the SOP.
Don’t just document the positive findings.
Check that all documents can be accessed quickly for inspection
Document any pre-established inclusion or exclusion criteria
Report any animal or subject that is not included
All analytic reports must be signed by and dated to the project manager.
Reports should not be destroyed after 5 years.
Archive documents so they are always available
You should be familiar with and up to date on all procedures (and any relevant SOPs).
If possible, ensure that you have the certificate and the qualifications necessary to perform this procedure.
Use good laboratory techniques and practices
Prepare for any emergency by being familiar with the Standard Operating Procedures (SOPs) and ready to follow them in an instant.
Make sure you have the Safety Data Sheet (SDS), for all chemicals that are used in your experiment
Use blood or urine to make sure that it is kept at the right temperature.
Assure that changes made to the experiments are either accounted or not affected by them.
